When I update Itunes, I am told to quit itunes. But it's not open

I cannot update Itunes or Garage band, becuase i get an alert saying that itunes must be closed first. However, it's not open. Nor is itunes helper open (as I closed it in the utility monitor).
Can anyone assist?
thanks

Thanks, but that wasn't it.
I finally figured it out. We have two accounts on this Apple Mac. And evn though the other account was logged out, it had Itunes Helper opened on it.
SO the resolution is to look through all accounts on the Mac and make sure all instances of Itunes (including Itunes helper through the Activity Monitor) are closed. Then the updates work.
Ahhhh. At last.

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