When opening Lightroom, get window saying it needs to quit.

Window comes up saying " Lightroom encountered an error reading from it's preview cache and needs to quit. Lightroom will attempt to fix this problem the next time it launches" However continually get the same result. Help please.

this happens because the preference pane is written in 32-bit and system preferences runs in 64-bit by default. so it needs to quit and restart in 32-bit every time you do this. you can set System preferences to always open in 32-bit. there is really no benefit in running it in 64-bit anyway.
go to the main Applications folder, select System preferences and enter command+i. in the popup check the box "open in 32 bit". that's it.
Message was edited by: V.K.

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