While installing latest update I lost ability to open Itunes.  Getting "runtime error" and then next box says error 1114.  Tried uninstalling and reinstalling and does not work.  Getting same error.  Very frustrating.

Cannot open Itunes after trying to install latest update.  Getting runtime error and then error 1114.  Tried uninstalling and reinstalling and still getting same error.  How do I fix this.  Very frustrating!

Hi there,
Earlier iTunes (and supporting applications) need to be completely uninstalled before you can install the new version. Here's the complete Apple info on this: http://support.apple.com/kb/HT1923
Mobile device application will most likely fail to uninstall, so you would need to visit its location(s) and manually delete the files then folder(s). The location of the folders is documented in this link from Apple.
It's a pain, but it should work.

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