White Screen, Grey Folder with Question Mark and no USB

Hello
I have a iMac, that is in a classroom of similar machines, they are running os v 10.4.6 (ish).
The mac in question had been reported with a fault so i went along to check it and this was a new fault for me.
When the mac boots, it bongs the hdd starts up and then a black white screen appears after a few minutes this changes to a white screen with a flashing grey folder with a question mark.
now reading on the forums, internet etc. i have found that maybe i should boot to disk. tried this but not disk activity.
next i read to boot into verbose mode at which point i find that the USB ports dont seem to be running so i can use a keyboard.
Anyone any ideas how i can troubleshoot this problem or why the problem occurred in the first place?
Thanks for any help offered.

This error indicates either that the internal HD has physical problems, or there is corruption on the drive (a failing directory or corrupt system files). You should boot from the Mac's original installation disk, run Disk Utility from the Utilities menu and do Repair Disk on the internal drive. If this fails to recover the drive, you may have to reinstall the system.
Matt

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