White screen when I turn the Satellite M50 on

I intermittently just get a white screen when I turn the computer on. Usually the problem is solved by switching the computer off and trying again - but sometimes I get a white screen again.
It seems to be connected to use of external devices - can anyone give me clear instructions about what should/should not be connected when I start and shut down the computer? Or any other suggested solutions?
Thanks

Thanks for your reply/advice - and the tip about Antivir. I used to use AVG and then Norton came as a package with this laptop....will have a re-think when my subscription need renewing.
I have updated the display/graphics driver but am still having the same problem of a white screen at boot-up. On reflection I think it is possibly a loose connection as I have just been a long trip with the laptop - including a fairly bumpy 4 hour bus ride - and I recall having the same problem several months ago which self-corrected after a similar trip (taking it down to a Toshiba ASP who never saw it as they were closed for the week-end and I had to get back to work!). This may sound strange but I took the laptop for a walk yesterday to see if any loose connection would shift and it then booted up on the second attempt rather than the 8th!
I guess I'll have to take it to the ASP - unfortunately it's no longer under warranty.
EDIT:
Problem solved. High temperature caused this issue
http://forums.computers.toshiba-europe.com/forums/thread.jspa?threadID=23402

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