Why can't I open pdf file?  Get a black box with a white x in the upper left hand corner that won't

Why can't I open pdf file?  Get a black box with a white x in the upper left hand corner that won't open either

I get the same thing... no matter what site i try to pull a pdf for IE10, it gives me the black x... if i use chrome it works, but my client does not want to use a different browser.
I followed the guide that Pat posted... nothing worked... I have uninstalled and reinstalled Java, Adobe reader, Adobe flash,.. upgraded to IE11, then back to IE10 due to medical software that is not compatable with IE11...
The kicker is that my Admin profile works just fine.. no issues.. so i know it has something to do with his profile....
Please.. someone... help!!!

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