Why does my guides dissapear after i save my pdf and open it again?

Why does my guides dissapear after i save my pdf and open it again?
Basically i use guides a lot when creating or editing PDFs, however when i am done editing and i save my work and close it. The next time i open up the pdf to edit, my initial guides when i created the Pdf is missing. This is really annoying. does anyone know how to fix this problem?

Yes go to preferences, and then click on security and privacy.

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Why does my guides dissapear after i save my pdf and open it again?

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