Why is my Mac Book Pro so slow?

Hi my Mac Book Pro is running really slow. It takes ages to perform simple tasks such as opening apps and doing basic jobs. I have run a check on the computer using Etresoft and the results are pasted below. Can anyone see anything wrong or have any suggestions?  I have run Disk Utility and all fine. I have also cleared out loads of files on the hard drive and moved to a external one. Thanks.
Problem description:
Slow mac when opening software and asking them to do simple tasks
EtreCheck version: 2.1.8 (121)
Report generated 19 February 2015 09:34:40 GMT
Download EtreCheck from http://etresoft.com/etrecheck
Click the [Click for support] links for help with non-Apple products.
Click the [Click for details] links for more information about that line.
Click the [Adware! - Remove] links for help removing adware.
Hardware Information: ℹ️
    MacBook Pro (13-inch, Early 2011) (Technical Specifications)
    MacBook Pro - model: MacBookPro8,1
    1 2.3 GHz Intel Core i5 CPU: 2-core
    4 GB RAM Upgradeable
        BANK 0/DIMM0
            2 GB DDR3 1333 MHz ok
        BANK 1/DIMM0
            2 GB DDR3 1333 MHz ok
    Bluetooth: Old - Handoff/Airdrop2 not supported
    Wireless:  en1: 802.11 a/b/g/n
    Battery Health: Normal - Cycle count 438
Video Information: ℹ️
    Intel HD Graphics 3000 - VRAM: 384 MB
        Color LCD 1280 x 800
System Software: ℹ️
    OS X 10.9.5 (13F34) - Time since boot: 1:27:14
Disk Information: ℹ️
    Hitachi HTS545032B9A302 disk0 : (320.07 GB)
        EFI (disk0s1) <not mounted> : 210 MB
        Macintosh HD (disk0s2) / : 319.21 GB (218.55 GB free)
        Recovery HD (disk0s3) <not mounted>  [Recovery]: 650 MB
    MATSHITADVD-R   UJ-898 
USB Information: ℹ️
    Apple Inc. FaceTime HD Camera (Built-in)
    Apple Inc. BRCM2070 Hub
        Apple Inc. Bluetooth USB Host Controller
    Apple Inc. Apple Internal Keyboard / Trackpad
    Freecom Freecom ToughDrive 750.16 GB
        USB 2 (disk1s1) /Volumes/USB 2 : 750.15 GB (496.90 GB free)
    Apple Computer, Inc. IR Receiver
Thunderbolt Information: ℹ️
    Apple Inc. thunderbolt_bus
Gatekeeper: ℹ️
    Mac App Store and identified developers
Adware: ℹ️
    Geneio [Adware! - Remove]
Kernel Extensions: ℹ️
        /Library/Extensions
    [not loaded]    com.caiaq.driver.NIUSBAudio4DJDriver (2.7.0 - SDK 10.9) [Click for support]
    [not loaded]    com.caiaq.driver.NIUSBHardwareDriver (2.7.0 - SDK 10.9) [Click for support]
    [not loaded]    com.caiaq.driver.NIUSBTraktorAudio2Driver (2.7.0 - SDK 10.9) [Click for support]
    [not loaded]    com.caiaq.driver.NIUSBTraktorKontrolS4Driver (2.7.0 - SDK 10.9) [Click for support]
        /Library/StartupItems/ArcanaStartupSound/Resources
    [not loaded]    arcana.PRAM (6.1) [Click for support]
        /System/Library/Extensions
    [not loaded]    com.caiaq.driver.NIUSBAudio2DJDriver (2.4.20) [Click for support]
    [not loaded]    com.caiaq.driver.NIUSBTraktorKontrolX1Driver (2.5.1 - SDK 10.7) [Click for support]
    [not loaded]    com.native-instruments.driver.NIUSBDeviceHelper (1.1.0 - SDK 10.7) [Click for support]
Startup Items: ℹ️
    ArcanaStartupSound: Path: /Library/StartupItems/ArcanaStartupSound
    Startup items are obsolete in OS X Yosemite
Launch Agents: ℹ️
    [not loaded]    com.adobe.AAM.Updater-1.0.plist [Click for support]
Launch Daemons: ℹ️
    [loaded]    com.adobe.fpsaud.plist [Click for support]
    [running]    com.macpaw.CleanMyMac2.Agent.plist [Click for support]
    [loaded]    com.microsoft.office.licensing.helper.plist [Click for support]
User Launch Agents: ℹ️
    [loaded]    com.adobe.AAM.Updater-1.0.plist [Click for support]
    [loaded]    com.adobe.ARM.[...].plist [Click for support]
    [failed]    com.apple.CSConfigDotMacCert-[...]@me.com-SharedServices.Agent.plist [Click for details]
    [loaded]    com.facebook.videochat.[redacted].plist [Click for support]
    [failed]    com.genieo.completer.download.plist [Adware! - Remove]
    [loaded]    com.genieo.completer.ltvbit.plist [Adware! - Remove]
    [failed]    com.genieo.completer.update.plist [Adware! - Remove]
    [loaded]    com.google.keystone.agent.plist [Click for support]
    [loaded]    com.macpaw.CleanMyMac2Helper.diskSpaceWatcher.plist [Click for support]
    [loaded]    com.macpaw.CleanMyMac2Helper.scheduledScan.plist [Click for support]
    [loaded]    com.macpaw.CleanMyMac2Helper.trashWatcher.plist [Click for support]
User Login Items: ℹ️
    Flux    Application  (/Applications/Flux.app)
    iTunesHelper    UNKNOWN Hidden (missing value)
    Microsoft AU Daemon    Application  (/Applications/Microsoft AutoUpdate.app/Contents/MacOS/Microsoft AU Daemon.app)
    Dropbox    UNKNOWN  (missing value)
    NIHardwareAgent    Application Hidden (/Library/Application Support/Native Instruments/Hardware/NIHardwareAgent.app)
Internet Plug-ins: ℹ️
    JavaAppletPlugin: Version: 14.9.0 - SDK 10.7 Check version
    FlashPlayer-10.6: Version: 16.0.0.305 - SDK 10.6 [Click for support]
    Default Browser: Version: 537 - SDK 10.9
    AdobePDFViewerNPAPI: Version: 10.1.13 [Click for support]
    AdobePDFViewer: Version: 10.1.13 [Click for support]
    Flash Player: Version: 16.0.0.305 - SDK 10.6 [Click for support]
    QuickTime Plugin: Version: 7.7.3
    SharePointBrowserPlugin: Version: 14.4.2 - SDK 10.6 [Click for support]
    Silverlight: Version: 5.1.10411.0 - SDK 10.6 [Click for support]
    iPhotoPhotocast: Version: 7.0 - SDK 10.8
Safari Extensions: ℹ️
    Ghostery
    NinjaKit
3rd Party Preference Panes: ℹ️
    Flash Player  [Click for support]
    Native Instruments USB Audio  [Click for support]
Time Machine: ℹ️
    Mobile backups: OFF
    Auto backup: NO - Auto backup turned off
    Volumes being backed up:
        Macintosh HD: Disk size: 319.21 GB Disk used: 100.66 GB
    Destinations:
        Time Machine Backups [Local]
        Total size: 0 B
        Total number of backups: 0
        Oldest backup: -
        Last backup: -
        Size of backup disk: Too small
            Backup size 0 B < (Disk used 100.66 GB X 3)
Top Processes by CPU: ℹ️
        41%    Live
        12%    WindowServer
         7%    coreaudiod
         2%    CleanMyMac 2
         2%    Adobe Photoshop Elements
Top Processes by Memory: ℹ️
    674 MB    Live
    228 MB    com.apple.WebKit.WebContent
    146 MB    CleanMyMac 2
    64 MB    mds_stores
    60 MB    Safari
Virtual Memory Information: ℹ️
    83 MB    Free RAM
    1.29 GB    Active RAM
    1.31 GB    Inactive RAM
    1.05 GB    Wired RAM
    1.04 GB    Page-ins
    32 MB    Page-outs
Diagnostics Information: ℹ️
    Feb 19, 2015, 08:04:58 AM    Self test - passed

When you see a beachball cursor or the slowness is especially bad, note the exact time: hour, minute, second.  
These instructions must be carried out as an administrator. If you have only one user account, you are the administrator.
Launch the Console application in any of the following ways:
☞ Enter the first few letters of its name into a Spotlight search. Select it in the results (it should be at the top.)
☞ In the Finder, select Go ▹ Utilities from the menu bar, or press the key combination shift-command-U. The application is in the folder that opens.
☞ Open LaunchPad and start typing the name.
The title of the Console window should be All Messages. If it isn't, select
          SYSTEM LOG QUERIES ▹ All Messages
from the log list on the left. If you don't see that list, select
          View ▹ Show Log List
from the menu bar at the top of the screen.
Each message in the log begins with the date and time when it was entered. Scroll back to the time you noted above.
Select the messages entered from then until the end of the episode, or until they start to repeat, whichever comes first.
Copy the messages to the Clipboard by pressing the key combination command-C. Paste into a reply to this message by pressing command-V.
The log contains a vast amount of information, almost all of it useless for solving any particular problem. When posting a log extract, be selective. A few dozen lines are almost always more than enough.
Please don't indiscriminately dump thousands of lines from the log into this discussion.
Please don't post screenshots of log messages—post the text.
Some private information, such as your name, may appear in the log. Anonymize before posting.

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