Why is this file locked (man chflags), does it need to be, and is it safe to unlock it?

Why is this file locked (man chflags), does it need to be, and is it safe to unlock it?
~/Library/Application Support/Adobe/Enterprise/Resources/Resource_3_1.db
Type this into a terminal in OS X, the above file appears to have a flag set to lock.
x-man-page://chflags

<the-sound-of-crickets>
The reason I'm asking, we have a bunch of computers we inherited that have some permissions issues within each user's respective home directory ("~"). The issue effects Acrobat Pro X's ability to launch ("Internal error occurred") since it tries to get access files/folders it doesn't have access to when the user launches. Recursively setting ownership to the respective user fixes the problem (and follows Apple's guidelines). However, that one file appears to have the unix file lock set (man chflags). So we are using a pre-installation script on our push policy to loop through every home directory. It appears the above file is the only one that won't let us change permissions.
Don

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