Why will iTunes not work on my computer?

I cannot get iTunes to work on my desktop computer. I had a crash some time ago and think it may have to do with a missing driver. I hope someone can help me with this problem. I can access iTunes on my laptop but it is not convenient.

What computer is it?
Have you tried to fully uninstall the program and reinstall it?
If it is Windows Based, try these articles to uninstall,
Removing and Reinstalling iTunes, QuickTime ... - Support - Apple
Removing and reinstalling iTunes, QuickTime, and ... - Support - Apple

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