Why will my iPhone 4S no longer sync?

My iTunes updated to 5.1.2 today.  I then connected my iPhone 4S to my PC and no sync happened.  My phone chirped and started charging, but iTunes did not open automatically.  I opened the program manually and again connected my phone, still same results.  I also tried turning my phone off and on.  Is there something wrong with the new update to iTunes? 

Thank you for your reply and your suggestion.  I did try using a different cable.  The original cable was one that had been working perfectly well just last week.  ITunes is still not styncing.

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