Why won't itunes open after being downloaded?

Please help I am about to cry with frustration! I have tried for a week to install itunes on my laptop for my new nano. The download seems to work but when I click on the icon itunes does not open. Quicktime works. I have tried uninstalling fully and then re-installing after re-starting but had no joy.
Can anyone help ?
Thank you

No error message at all. Hourglass appears for a few seconds and then nothing.
I don't have Norton and have tried disabling my virus software and then running it but still nothing.
Ahhh, thank you kindly. that's already ruled out a couple of possible culprits.
One last preliminary question aimed at diagnosing the issue prior to trying a treatment.
reboot the PC. bring up your Task Manager, and click on the "Processes" tab. now try to launch itunes again.
does an "itunes.exe" process appear in the Processes tab? if so, does it persist in there or does it disappear after a few seconds?

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