Why won't Twain source open.

PSE 1.0.1 has been working great forever. Then my computer crashed and I restored a copy of my C drive. Now PSE won't open Epson Twain for import (Epson 1650 scanner), which had worked great before. EPSON TWAIN 5 shows in the IMPORT menu, but when I click on it I get this error:
"Could not open the Twain source. Make sure there is a valid source for your scanner in the Twain directory found in the Windows directory."
I reinstalled Epson Twain from disc twice with no good results.
In my TWAIN_32 directory there are files wiatwain.ds, ESTW5.ds, among others, and a subdirectory EPFB5 containing ESTW5.ds and others. I don't really know what a "valid source" for my scanner is.
Can anyone advise? Thanks.

Hi,
Please try uninstalling/ reinstalling the scanner drivers. Also, please check the cables are connected properly.
Thanks/Tarun

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Wow! A lot of ifs, ands, and maybes here.
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The indiscriminant installation of additional codecs often creates more problems than it solves owing to the logrithmic increased potential for the introduction of QT codec component conflicts. The normal "rule of thumb" here is to identify a missing codec and to then install only that specific codec component. Even then, there is a possibility that there may be a conflict but at least it is more easily identified so you can better evaluate which of the conflicting codecs to leave installed and which to swap only when needed/required. As to the use of MPEG Streamclip, it basically uses your system's QT component configuration of access of most codecs as opposed to VLC and HandBrake which contain their own, built-in codec support. So if QT is having a problem, it is often likely that MPEG Streamclip will also have problems.
I tried opening one of these .mp4 files in Handbrake (0.9.8) and it was able to open and convert the file to an .mp4 that is then openable in QT 10 with a format of H.264, AAC, and a reduced frame rate of 29.84. However, this doesn't seem like a good solution because it takes about 2 hours to convert a file with 30 minutes of video. I just want to be able to trim these big files down to some short video clips that are in an accessible format.
The HandBrake workflow forces a recompressing of the file data which is why it takse so long. That is why I suggested you try deleting any extraneous data tracks found in the source MP4 file container using QT 7 Pro and then use the "Save" or "Save As..." option to re-write the original audio and video data to a new MOV file container which takes much less time.
Am I missing the right codec? Or, as I'm beginning to wonder, is this format one that is too demanding for OS 10.6.8 and QT 10 and they just cannot handle it no matter what codecs I have on my computer (because of the 60 fps frame rate? Or is it the subtitle track?). Or is the solution to upgrade my operating system to Mountain Lion (10.8) and QT 10.2? My 15" MacBook Pro is about 2 years old with a 2.66 GHz Intel Core i7 and 4 GB of RAM (1067 MHz DDR3).
Probably not. The VLC reported data rate may either indicate the MP4 content is AVCHD/BD sourced or it is reading interlaced content as progressive which I have noted it can do on occasion when I compare the media info as read by various different apps and/or utilities. Since you indicate the file opens in Mountain Lion, my guess would be that your MP4 content is actually AVCHD/BD sourced since such support was only recently added to Mac OS X v10.8 software. As to moving up to Mountain Lion, as always, that is something you would have to evaluate for yourself. For instance, do you require PNG compression for video content? By default you would lose it under Mountain Lion and have to re-enable it manually if needed. Are there other pros and cons that you need to consider before upgrading to Mountain Lion? These are the types of questions and compatibility issues that only you can answer for yourself.

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