Will 16GB RAM wear out the SSD? rMBP

Will 16GB RAM in my 2014 Retina Macbook Pro wear out the SSD? I plan on keeping it for 4 years.
Can the SSD, seeing how as the new Macbooks have everything soldered I think, be replaced at all if it runs out of write cycles?

The SSDs of today have a Mean Time Between Failure rate equal to that of the hard drives.  That means you can use the modern SSD as much as you like as those failure rates are in many, many years.  The first and second generation SSDs had vey short lifetimes.  All of that has changed and you can feel free to use it as much as you like.
Your other comment, the current generation of Mac OS X's, Lion, Mountain Lion and Mavericks, do grab a great deal of the available installed memory.  So it looks as though all of the memory is in use.  Actually it is not but is simply grabbed by the OS X so it can quickly allocate memory as needed.  More important to look at than the available memory is the Memory Pressure.  Go to Applications > Utilities > Activity Monitor and click on Memory top center of the window.  Then look at the Memory Pressure bottom center.  As long as that is displayed as green you are great.  Yellow and you are loading up the memory.  Red and you are using virtual memory, the SSD, for swap space.  With 16 GB ram it is not likely you will ever see that go yellow.
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