Will a SATA III Hard Drive work on a Mac Pro 2,1 (2008)

Will a SATA III work on a Mac Pro 2,1 (I think 2008)?
http://www.amazon.com/gp/product/B004CSIG1G/ref=wms_ohs_product?ie=UTF8&psc=1
If not the above, then what?

Apple Pro RAID card is not compatible with 3TB drives and never will be it now seems. It also lacks any real performance and is destined where RAID 5 is a must.
SSDs are a more interesting matter in choice and support... but not traditional platter type drives.
I use SSD for system now 100% on multiple systems, 10K WD VR ($200 for 1TB / 180MB/sec and variety of WD blacks and Green.
2008 has some interesting stuff, PCIe mix and support and booting, but more choices in GPU. Runs best with all 8 DIMM slots filled. Was the first to have UEFI to support 64-bit kernel but does not support industry standard enough to support Windows 8 UEFI.
Storage market would be a total mess like it was back in 2004 when SATA 1.0 moved to 2.0 and lots of problems. SATA 1.0 in early G5 was just PATA with an SATA interface chip slapped on and not "native" SATA. THAT is where the "will the IBM Hitachi or Seagate or Maxtor" really did require research. Not with Mac Pro line 2006 and on.

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