Will new USB hard drive work in Safe Mode?

Hello,
I just a had a recent post about some Toshiba laptop issues I am having.  To make sure I don't lose my files, I have have been looking at a Western Digital 500GB USB drive. 
I'm able to boot to Safe Mode OK, and USB thumb drives have worked.  I noticed this WD USB drive has software to install.  Will I be able to use the USB hard drive for the first time in Safe Mode, or will I need to install the software first (which I don't think I'll be able to do in Safe Mode).
Just making sure I can before I buy it, thanks!
Solved!
Go to Solution.

you should not have any problem installing the WD software in safe mode and perform the backup.
L305-S5955, T9300 Intel Core 2 Duo, 4GB RAM, 60GB SSD, Win 7 Ultimate 64-bit

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