Windows 7 Desktop error message "Can't initialize plugins directory" - Blocked from Installing/uninstalling anything

Blocked from running *.exe
files. Blocked in Control Panel from Uninstalling anything. 
Consistently returns: "Can't initialize plugins directory"
What I tried:
1. Safe Mode with Network
2. File cleanup from C Drive Tools
3. Environmental variable: changed
to this c:/TEMP
c:/TMP (Created TEMP folder
on
directory tree.)
4. Googled error-- known
issue but fixes do not work. (Created New Profile, SFC Scan
of Windows files, moved TEMP folder,
etc)
5. Run as administrator
6. Started after the support desk for ACT client management software uninstalled SQL to restore access to a CLIENT database that was lost for reasons unknown. So it appears some damage was done.
Question is, what was damaged and how to fix it, if this caused this problem and it was not malware fiddling with
registry. 

Hi,
You can open Control Panel\System and Security, click
Event Viewer under Administrator Tools to check if some logs record recent errors.
Also you can start computer and typing F8, click Repair Your Computer to perform
System Restore.

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