Windows cannot find C:/users/****/appdata/local/adobe/oobe/pdapp/dwa/setup.exe

I am trying to load Adobe Photoshop CS5 and get the message:
Windows cannot find C:/users/****/appdata/local/adobe/oobe/pdapp/dwa/setup.exe
Can someone please help. I am a novice so please give step by step instructions.

how are you trying to install?
downloaded files?  files on an installation disk?
are you changing any default installation settings?
when do you see that message?

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