Wireless mouse has to be connected with every startup of imac

Hi,
I asked this a few days ago and marked it answered but unfortunately it's still happening. Here's the snapshot:
Wireless Magic Mouse shows as paired with my iMac. But at most startups, iMac doesn't connect to it. Cursor remains dead in upper left corner.
After a minute or so, the Assistant process starts. I have to flip the switch on the mouse to get it to recognize mouse. Then it connects and works.
I did try unchecking the first option in the Bluetooth Prefs > Advanced screen ("Open Bluetooth Setup Assistant at startup when no input device is present.") But when starting up this a.m., the cursor was immovable and no Assistant process startup so I had to plug in a usb mouse to connect.
Any other thoughts on why this may be happening? How to solve?
If I happen to be there to move the mouse first thing when iMac is turned on, it sometimes works normally (moves!). But you know how it is, sometimes you turn on a computer and do other things for awhile. If no solution, I can always keep doing as I am, but hope to find the answer to this quandry!
Thanks so much for any insight!

What about the Advanced option to allow a device to wake up the computer? Is that option turned off?
Are you turning the mouse off (I'm assuming the mouse has its own on-off switch which may be wrong since I don't actually own one.) The mouse must be turned on before the computer turns on.
I've sometimes found issues with BT devices simply not connecting easily if separated too far from the computer, especially if the computer is housed in a metallic case. The BT range seems to be more limited than expected. This can be a problem with the BT antennae and/or there placement within the computer housing.

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