With out restart, My MacBook MA255 can't working over 48hours.

From 6 months ago, My MacBook MA255 can't work over 48hours.
When it is works over 24hours, Finder will go to no response.
Force Quit can't help me to relunch Finder.
Parallels still working, but no internet connect.
If I click something, the whole computer will go to no response(keyboard and touch pad).
At that time I have to Forced it shutdown.
I also reinstalled OS but the problem is continue.
and I can't find any error from logs.

Hey Yu Su & welcome to the forums.
If you've reinstalled the OS and are still having issues, your hard drive could be failing. Bring the computer to an Apple store and ask the folks there to diagnose it for you.
~Lyssa

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