Without PR create a new PO is possible,but i want with out PR create PO

Dear sir
without PR create a new PO is possible,but i want with out PR create PO is not Possible,that setting please provide

Dear,
Make PR entry mandatory for ME21N transaction.
Check: PR mandatory in PO Creation ME21N and ME22N
Regards,
Syed Hussain.

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1. Do we need to have any application server in my
side if we get the certificate from CA? Can't we have
that certificate installed in my windows system.?Yes
2. When getting the certificate from CA, I hope we
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Without PR create a new PO is possible,but i want with out PR create PO

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