Yosemite 10.10.2 freezes my keyboard and mouse on my Mac Pro

I own a Mac Pro (Late 2009), 2GHz Quad-Core Intel Xeon, 3GB memory 1066 MHz DDR3 ECC, NVIDIA GeForce GT 120 512 MB graphics card.
Ever since the latest Yosemite upgrade (10.10.2), my computer will boot up fine, but within a minute or so, the mouse and keyboard are no longer responsive. The computer still runs in the background—Google Drive updates, browser windows open, the shutdown window pops up when I press the power button—but I can't move the mouse or make the keyboard work.
The keyboard is wired, but the problem persists whether I plug it into a different USB port or not. I have tried both my Bluetooth mouse (a brand-new Logitech Anywhere MX) and an older corded Magic Mouse, but neither works. I've unplugged the Bluetooth dongle for the MX to see if that's causing the problem and tried the Magic Mouse in other USB ports, also to no avail.
Starting the computer in Safe Mode eliminates the freezing, so I suspect the problem is not a fatal or unfixable one.
How can I trace the source of this problem? I haven't found others having similar issues.
Thanks in advance!

You are most welcome.
Barry

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