After Mavericks, applications tend to become slow, painfully slow. Particularly iMovie; all other applications, Mail, Browser (Chrome) and others too are either running slow or 'not responding'. Help, please

After upgrading to Mavericks, from Mountai Lion, all applications are slowing down. iMovie particularly is painfully slow. When iM is running, any other application that is opened up also runs slow or does not respond altogether. It was fine before Mavericks, can somebody help, please.
Thank you.

Please read this whole message before doing anything.
This procedure is a diagnostic test. It’s unlikely to solve your problem. Don’t be disappointed when you find that nothing has changed after you complete it.
The purpose of the test is to determine whether the problem is caused by third-party software that loads automatically at startup or login, by a peripheral device, or by corruption of certain system caches. 
Disconnect all wired peripherals except those needed for the test, and remove all aftermarket expansion cards. Boot in safe mode and log in to the account with the problem. Note: If FileVault is enabled on some models, or if a firmware password is set, or if the boot volume is a software RAID, you can’t do this. Ask for further instructions.
Safe mode is much slower to boot and run than normal, and some things won’t work at all, including sound output and  Wi-Fi on certain models. The next normal boot may also be somewhat slow.
The login screen appears even if you usually log in automatically. You must know your login password in order to log in. If you’ve forgotten the password, you will need to reset it before you begin. Test while in safe mode. Same problem? After testing, reboot as usual (i.e., not in safe mode) and verify that you still have the problem. Post the results of the test.

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