Any known issues when programatically opening PDFs in Protected Mode on Windows 7?

Hi all,
We are a small development team that produces a Windows application that generates medical reports using a third party PDF library (PDF Creator Pilot) that are then automatically launched using the recommended Adobe Reader.
I've come across a seemingly random problem with opening PDFs when Protected Mode is enabled, and I'm finding it hard to reproduce this field complaint so am wondering if there was any known workaround or if anyone has had similar issues.
The problem occurs when we try to programatically open the PDF by a Win32 system call as follows, "ShellExecute(NULL, "open", "some_file.pdf", NULL, NULL, SW_SHOWNORMAL);". In some cases we have complaints that nothing at all occurs when Adobe Reader should actually be launched, and sometimes the dialog as described in "http://helpx.adobe.com/acrobat/kb/protected-mode-troubleshooting-reade r.html" appears. In all cases, if the users disable Protected Mode in Adobe Reader the problem goes away. We've checked this troubleshooting guide and nothing in there seems to help our users so their problems persist.
It should be noted that this was observed in both Adobe Reader X and XI.
Any help is greatly appreciated,
Chris.

Thanks Pat!
I've created the same question on the SDK forum so if anyone has any answers please reply there as it could also help other users.
http://forums.adobe.com/thread/1174517
Much thanks,
Chris

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