Exchange Server bounce back when external Client's email the business.

Hi, 
One of our clients are having a small issue and I have been unable to pin this down. The businesses Broadband line was changed over to Fibre a week ago and since then, some of their clients are having an issue emailing our client.
When client's email the business they are receiving the below error. Not all clients are having an issue sending & there is no logical pattern to it.
'The server has tried to deliver this message, without success, and has stopped trying. Please try sending this message again. If the problem continues, contact your helpdesk'
My colleague switched the line over and updated all the relevant records where the domain is hosted. One thing we have noticed is that everyone in the business is receiving a stupid amount of spam emails now.
Any suggestions or help is appreciated.
Thanks,
Alex
EDIT: The client is running exchange 2010.

Hi,
Although correctly updating MX Records resolved a few issues with emails, not everything is fixed.
3 Clients still have issues emailing us and receive the following bounce back:
Delivery has failed to these recipients or groups:
[email protected]
The server has tried to deliver this message, without success, and has stopped trying. Please try sending this message again. If the problem continues, contact your helpdesk.
Diagnostic information for administrators:
Generating server: EARTH.fccparagon.local
[email protected]
#550 4.4.7 QUEUE.Expired; message expired ##
Original message headers:
Received: from P000014 (192.168.110.14) by EARTH.fccparagon.local
 (192.168.110.20) with Microsoft SMTP Server id 14.0.722.0; Fri, 10 Oct 2014
 14:38:14 +0100
Date: Fri, 10 Oct 2014 14:38:14 +0100
From: "[email protected]" <[email protected]>
To: <[email protected]>
Message-ID: <[email protected].20>
Subject: Smart Rental Protection Payment Application PIN374121/01
MIME-Version: 1.0
Content-Type: multipart/mixed;
boundary="----=_Part_77516_238539778.1412948294165"
X-Mailer: ColdFusion 9 Application Server
Return-Path: [email protected]
X-EXCLAIMER-MD-CONFIG: f2e42f62-f17e-4c46-b896-06fbe0c96e5c
Regards, Alex

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