IE 8 "Runtime Error" trying to open PDF with Reader 9.5.1

I've seen many variants of this problem on the forum.  Running Win7, IE 8, Firefox 14, and Reader 9.5.1.
For some little while, I've had a problem opening PDF files from links on Webpages that I view in IE8.  I see the following Runtime Error message:
More recently, I've seen a similar problem with Firefox 14.  The difference is that there's no error message with Firefox ... it opens a new tab, but the browser tab remains blank.
Could the problem be from installing Reader 9.5.1 recently?  How do I back out that update, and resort to the previous version of Reader -- which ran error free?
Thanks
Jerry

We created a small standalone test application, which just opens a PDF. Same issue was found, with just this one User. Here's the code:
<?xml version="1.0" encoding="utf-8"?>
<s:WindowedApplication xmlns:fx="http://ns.adobe.com/mxml/2009"
        xmlns:s="library://ns.adobe.com/flex/spark"
        xmlns:mx="library://ns.adobe.com/flex/mx"
        width="1004" height="510" backgroundColor="#000000" creationComplete="windowedapplication1_creationCompleteHandler(event)">
<fx:Script>
  <![CDATA[
   import mx.events.FlexEvent;
   protected function windowedapplication1_creationCompleteHandler(event:FlexEvent):void
    myHtml.location = "vt1_04_using_flash_builder.pdf";
  ]]>
</fx:Script>
<fx:Declarations>
  <!-- Place non-visual elements (e.g., services, value objects) here -->
</fx:Declarations>
<mx:HTML id="myHtml" left="10" right="10" top="10" bottom="10"/>
</s:WindowedApplication>

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