ITunes not running on Windows XP

I've downloaded the latest version of iTunes. It worked the first few times I ran it, but then all of a sudden it refused to open when I clicked it. I get a message saying "iTunes has encountered a problem and needs to close. We are sorry for the inconvenience." Then I have the options of debug, Send error report, dont send error report. I've re-downloaded and installed iTunes several times now and I still get the same message, any ideas as to whats going on?
  Windows XP  

I had a similar issue - iTunes using ~40% of cpu when playing audio. I had a brain flash the other day, and remembered that when going through the Quicktime Preferences I had set the audio format for my soundcard (M-Audio Revolution 7.1) at 24 bit/192kHz. I had thought the setting was asking for the maximum capability of the card. In fact, what it says is "Select the output format supported by your audio hardware." After a little detective work, I realized that this setting was causing iTunes and Quicktime to up-convert everything to 24/192. Since 99% of what I play in iTunes is encoded natively at a sampling rate of 44.1kHz (mp3,AAC) I went ahead and changed the audio format to 24/44.1 in the QT preferences. iTunes now uses less than 10% of my cpu. Hope this helps!

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