Just got an error when updating Itunes.. can anyone advise on a solution?

The updater has been popping up for a while but i'v been fobbing it off. Finally updated today.After updating I went onto Itunes and an error came up, it said:
'Itunes cannot run because some of its required files are missing. Please reinstall Itunes'.
I reinstalled Itunes, then reset the computer but the problem still remains. Can anyone offer any useful advice on how to overcome this prodigious annoyance.
Thanks

Hello,
Yes I used the apple software updater and it also installed quicktime or realplayer (i always confuse the two).
I followed that link, clicked repair, went through the process etc etc.. it told me Itunes has been successfully installed on your computer
I clicked the Itunes icon on my desktop and got the same error message as before?
The only thing that I can think of is that when I used Spotify, Itunes went a bit weird, and since then it has not been operating as normal. I could be clutching at straws, but that's all I can put it down to.
Can you offer any other advice?
Thanks.

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