Mouse left-click not working after first click

I see this issue has been up several times. I have disabled Microsoft .NET Framework Assistant and Java Quick Starter, but still have the problem. I’m using the lastest FF ver. 3.6.6 on Win XP. I think I have had this problem once in a while since FF 3.0 but now it’s almost daily.
Does anyone know what’s causing this?
Thanks,
Frank
== User Agent ==
Mozilla/4.0 (compatible; MSIE 7.0; Windows NT 5.1; GTB6.5; .NET CLR 1.1.4322; InfoPath.1; .NET CLR 2.0.50727; .NET CLR 3.0.4506.2152; .NET CLR 3.5.30729; .NET4.0C; .NET4.0E)

I replaced my wireless mouse with a wired one, and the problem went away.

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