Sales UI not working for ABAP transaction

Hi All,
I am wokring on SALES UI and created a roles copying role Internal Sales represnatative. I have added ABAP transactions like VA01 and XD01 along with WEBDYNPRO  transactions. While Webdynro applications are working fine but when trying to use ABAP transations screens are appearing  but unbale to select filed values or tabs or exceute. Almost screens are freezed. Both  are working fine in development client but when moved to testing client ABAP transactions are not working.
We are unable to find the cause. i have activated error log on internet explorer i am getting following errors:
The value of the property 'append_to_body' is null or not defined, not a function object
and
UCF properties is undefined
Lightspeed.js
code : 0
URI:http://xxxxxxxxxx:8000/sap/public/icmandir/its/ls/js/lightspeed.js?201
Can anyone let me know the root cause and remedy for the issue.
Thanks and Regards
Satya

Satya
   Assuming that this is not a security issue, then I will assume this is a probably a rendering issue cause by the IE Lightspeed cache. The cache itself could resides either at your desktop, MIME directory server or the App Server; and it would need to be re-initialize for it to function.  Good luck!
Step 1: Clear your IE Cache by deleting all your IE Temporary Files
-> If this fail to work, try step 2.  
Step 2 below need to be thoroughly tested before repeat in PRD environment, It could cause any user session that is accessing the MIME object to crash
Step 2: Clear the MIME Directory (REF: SAP Note - 1922663)
-> Run the report WDG_MAINTAIN_UR_MIMES in order to update the archive containing the MIME files for HTML rendering. Choose deploy MIMES.
-> If this fail to work, try step 3  
Step 3 below should only be used in NON-PRD environment AND work with your Basis Team to ensure that it will not cause issue
Step 3: Clear the Server \ App Server Mime
-> Run SE38, program RSMONICM, click execute twice then use the drop down menu path below:
Goto --> HTTP Plugin --> Server Cache --> Invalidate Globally. Click "Yes".

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