Why am i getting mouse lag after wake from sleep?

both cordless mmouse and corded wacom tablet are displaying lag after waking from sleep.  restart usually, but not always, helps.  usb devices are on a powered external hub.  noticing this after upgrading from nvidia geforce 8800 to ati 5770.  compatibility issue?
specs are:
Hardware Overview:
  Model Name:          Mac Pro
  Model Identifier:          MacPro3,1
  Processor Name:          Quad-Core Intel Xeon
  Processor Speed:          2.8 GHz
  Number Of Processors:          2
  Total Number Of Cores:          8
  L2 Cache (per processor):          12 MB
  Memory:          8 GB
  Bus Speed:          1.6 GHz
  Boot ROM Version:          MP31.006C.B05
  SMC Version (system):          1.25f4
ATI Radeon HD 5770:
  Name:          ATY,Hoolock
  Type:          Display Controller
  Driver Installed:          Yes
  MSI:          Yes
  Bus:          PCI
  Slot:          Slot-1
  Vendor ID:          0x1002
  Device ID:          0x68b8
  Subsystem Vendor ID:          0x106b
  Subsystem ID:          0x00cf
  Revision ID:          0x0000
  Link Width:          x16
  Link Speed:          5.0 GT/s
NVIDIA GeForce GT 120:
  Name:          NVDA,Display-B
  Type:          Display Controller
  Driver Installed:          Yes
  MSI:          Yes
  Bus:          PCI
  Slot:          Slot-2
  Vendor ID:          0x10de
  Device ID:          0x0640
  Subsystem Vendor ID:          0x106b
  Subsystem ID:          0x0010
  ROM Revision:          3386
  Revision ID:          0x00a1
  Link Width:          x16
  Link Speed:          5.0 GT/s

That's normal. It just lets you know the call has ended.

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