" in column, need them removed

When I imported an Excel sheet into a table that was TAB delimited, some fields have "" quotes "around the values", I need to remove them from the 2 fields in my table, the sample data would be:
"FirstName, LastName"
and different names of course, what is the best way to UPDATE the table to remove those ?
Thank you.

Yes, I used the SQL*LDR and I did not have the OPTIONALLY enclosed by, learned by lesson, but it is too late to re-do that process :- )
I need to fix the table, only 2 columns are affected by this.
I want to take the value, say: "Tom, Richardson" and strip the " and replace it with: Tom, Richardson
that first SQL that I used seemed to do the trick, now I have to deal with those tab instances, that's weird, but a learning lesson for me.

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