After my update of Mountain Lion, my MacBook Pro has been slow and failed multiple times. I've had to restore at least 10 times in the past two weeks.

Question

Here's my EtreCheck info:
Hardware Information:
          MacBook Pro (15-inch, 2.53GHz, Mid 2009)
          MacBook Pro - model: MacBookPro5,4
          1 2.53 GHz Intel Core 2 Duo CPU: 2 cores
          4 GB RAM
Video Information:
          NVIDIA GeForce 9400M - VRAM: 256 MB
Startup Items:
          HP IO - Path: /Library/StartupItems/HP IO
          HP Trap Monitor - Path: /Library/StartupItems/HP Trap Monitor
          PenTabletDriver - Path: /Library/StartupItems/PenTabletDriver
System Software:
          OS X 10.8.4 (12E55) - Uptime: 0 days 0:15:20
Disk Information:
          FUJITSU MJA2250BH FFS G1 disk0 : (250.06 GB)
                    disk0s1 (disk0s1) <not mounted>: 209.7 MB
                    Macintosh HD (disk0s2) /: 249.2 GB (41.93 GB free)
          HL-DT-ST DVDRW  GS23N 
USB Information:
          Apple Inc. Built-in iSight
          Apple Internal Memory Card Reader
          Apple Inc. Apple Internal Keyboard / Trackpad
          Apple Computer, Inc. IR Receiver
          Apple Inc. BRCM2046 Hub
                    Apple Inc. Bluetooth USB Host Controller
FireWire Information:
Thunderbolt Information:
Kernel Extensions:
          at.obdev.nke.LittleSnitch          (2.5.4)
Problem System Launch Daemons:
Problem System Launch Agents:
Launch Daemons:
          [loaded] at.obdev.littlesnitchd.plist
          [loaded] com.adobe.fpsaud.plist
          [loaded] com.adobe.SwitchBoard.plist
          [loaded] com.autodesk.backburner_manager.plist
          [loaded] com.autodesk.backburner_server.plist
          [loaded] com.autodesk.backburner_start.plist
          [loaded] com.google.keystone.daemon.plist
          [loaded] com.intego.commonservices.daemon.plist
          [loaded] com.intego.commonservices.icalserver.plist
          [loaded] com.intego.commonservices.metrics.kschecker.plist
          [loaded] com.intego.netupdate.daemon.plist
          [loaded] com.intego.task.manager.daemon.plist
          [failed] com.intego.VirusBarrier.daemon.plist
          [failed] com.intego.VirusBarrier.logger.daemon.plist
          [failed] com.intego.VirusBarrier.scanner.daemon.plist
          [loaded] com.novatelwireless.mobilink3.plist
          [loaded] com.novatelwireless.NvtlServer.plist
          [failed] com.starfield.backupservice.plist
          [loaded] com.wdc.WDDMservice.plist
          [loaded] com.wdc.WDSmartWareServer.plist
Launch Agents:
          [loaded] at.obdev.LittleSnitchNetworkMonitor.plist
          [loaded] at.obdev.LittleSnitchUIAgent.plist
          [not loaded] com.adobe.AAM.Updater-1.0.plist
          [loaded] com.divx.dms.agent.plist
          [loaded] com.divx.update.agent.plist
          [loaded] com.epson.eventmanager.agent.plist
          [loaded] com.google.keystone.agent.plist
          [loaded] com.intego.commonservices.statusitem.plist
          [loaded] com.intego.netupdate.agent.plist
          [loaded] com.intego.task.manager.notifier.plist
          [loaded] com.intego.VirusBarrier.alert.plist
          [failed] com.visionobjects.Axiotron.Quickscript.login.plist
          [loaded] com.wacom.pentablet.plist
          [failed] com.wacom.wacomtablet.plist
User Launch Agents:
          [loaded] com.akamai.client.plist
          [failed] com.apple.CSConfigDotMacCert-[redacted]@me.com-SharedServices.Agent.plist
          [loaded] com.divx.agent.postinstall.plist
User Login Items:
          uHD-Agent
          AdobeResourceSynchronizer
          vzwwirelessd
          CrossOver CD Helper
3rd Party Preference Panes:
          Flash Player
          Flip4Mac WMV
          Growl
          Java
          MacFUSE
          NetUpdate
          Perian
          PenTablet
          WacomTablet
Internet Plug-ins:
          AdobePDFViewer.plugin
          DivXBrowserPlugin.plugin
          Flash Player.plugin
          FlashPlayer-10.6.plugin
          Flip4Mac WMV Plugin.plugin
          googletalkbrowserplugin.plugin
          iPhotoPhotocast.plugin
          JavaAppletPlugin.plugin
          npgtpo3dautoplugin.plugin
          o1dbrowserplugin.plugin
          OVSHelper.plugin
          QuickTime Plugin.plugin
          Unity Web Player.plugin
          WacomNetscape.plugin
          WacomTabletPlugin.plugin
User Internet Plug-ins:
          BlueStacks Install Detector.plugin
          fileEditTool64_15.plugin
Bad Fonts:
          None
Top Processes by CPU:
              14%          Safari
               4%          WindowServer
               1%          EtreCheck
               1%          Little Snitch Network Monitor
               1%          hidd
               0%          configd
               0%          mds
               0%          DivXMediaServer
               0%          mDNSResponder
               0%          lsd
Top Processes by Memory:
          131 MB             WebProcess
          123 MB             Safari
          74 MB              Dock
          74 MB              WindowServer
          70 MB              CrossOver CD Helper
          61 MB              mds
          41 MB              coreservicesd
          29 MB              SystemUIServer
          25 MB              Finder
          20 MB              PluginProcess
Virtual Memory Statistics
          1.84 GB            Free RAM
          1.23 GB            Active RAM
          164 MB             Inactive RAM
          525 MB             Wired RAM
          387 MB             Page-ins
          0 B                Page-outs
Any guidance would be very appreciated! My little MacBook has been a very good machine up until recently.

Answer 1

Please read this whole message before doing anything.
This procedure is a diagnostic test. It’s unlikely to solve your problem. Don’t be disappointed when you find that nothing has changed after you complete it.
The purpose of the test is to determine whether the problem is caused by third-party software that loads automatically at startup or login, by a peripheral device, or by corruption of certain system caches. 
Disconnect all wired peripherals except those needed for the test, and remove all aftermarket expansion cards. Boot in safe mode and log in to the account with the problem. Note: If FileVault is enabled on some models, or if a firmware password is set, or if the boot volume is a software RAID, you can’t do this. Ask for further instructions.
Safe mode is much slower to boot and run than normal, and some things won’t work at all, including sound output and  Wi-Fi on certain iMacs. The next normal boot may also be somewhat slow.
The login screen appears even if you usually log in automatically. You must know your login password in order to log in. If you’ve forgotten the password, you will need to reset it before you begin. Test while in safe mode. Same problem? After testing, reboot as usual (i.e., not in safe mode) and verify that you still have the problem. Post the results of the test.