After upgrading to the latest version of itune, I get this message when trying to open itunes: "The I'tunes Library File is locked, on a locked disk, or you do not have permission to write for this file.

After importing the latest version of itune, I now get this message:  "The I-tunes library file is locked, on a locked disk , or you do not have permission to write for this file.  How do I resolve this?

check if you have read & write permissions for your music folder. in the finder, right-click on it and get info. unlock the little padlock (you may have to enter your admin password) and change the permission settings if necessary. next, click on the little gear-shaped icon and apply to enclosed items like so
the important part is to apply to enclosed items !
also, even if it seems unrelated, try the steps in this support article: iTunes: Missing folder or incorrect permissions may prevent authorization

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