Cannot initialize photoshop disk not available.

I have 3 HD's. My Mac OS runs on HD 1 as well as my applications.  I use HD 1 & 2 as storage for photos and video. I switched my scratch disc order to HD 2 and HD 3 but clicked off HD 1 as a scratch disk in photoshop extended CS4.  Now I cannot open photoshop not even to reset my scratch discs.  It will not open because it says it cannot initialize photoshop because disk is unavailable.  The weird part is that I cannot open photoshop in CS3 because of the same reason even though I did not touch that.  I uninstalled and reinstalled both from disk and time machine but does not help.  How do I change back to what I had before I screwed this up.  I can't believe the program allows itself to be obstructed so easily without any warning.
Thanks
Scott

Go back in Time Machine to before you did this and restore the Photoshop folders and preferences in the HD\Library\Preferences, HD\Library\Application Support\Adobe, and Home\Library\Preferences folders.
Or you can just dump the preferences and then try to restart PS.
I suggest the Time Machine method in case you have custom workspace settings or paths you don't want to lose and have to reset

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