DataSource No Longer Fills Data Calls VB 2010

Question

I am using a DataSource in my form app, and it was working fine for calls made across the board, Fill, Add, Delete, etc... It suddenly stopped working. I get no errors on build, no data is added to any ComboBoxes, and no new Adds work either.
I created a new DataSource from the same database that works fine with the exact same connection. The location of the database never moved, no changes were made to any properties of the DataSource or any of the Adapters assigned to the source, it just stopped
working. Here is some screen shots and code of my form.
I tried to do a Code Compare but since there are a bunch of Adapters assigned to the source I can't find any anomalies. What would kill a data connection so that the code still sees the connection, but nothing gets filled?
The following code no longer works, no Fill or Add to DCGDataSet;
Private Sub Form1_Load(sender As System.Object, e As System.EventArgs)
'TODO: This line of code loads data into the 'DCGDataSet1.Main' table. You can move, or remove it, as needed.
Me.MainTableAdapter.Fill(Me.DCGDataSet.Main)
Me.MainTableAdapter.Fill(Me.DCGDataSet.Main)
'comboClear()
End Sub
Private Sub btnAddNew_Click(sender As Object, e As System.EventArgs)
' Add new Job to the database
Dim newJobRow As New DCGDataSetTableAdapters.MainTableAdapter
Dim intInsert As Integer
Dim jobText = txtBoxAddNewJob.Text
intInsert = newJobRow.InsertJob(jobText)
If intInsert = 1 Then
MessageBox.Show("New Job Added")
' Update the comboBox values
Me.MainTableAdapter.Fill(Me.DCGDataSet.Main)
txtBoxAddNewJob.Text = ""
clearTabOne()
Else
MessageBox.Show("Job Not Added")
End If
End Sub
The following call for a ComboBox works fine, this is the new DataSource;
Private Sub MainForm_Load(sender As System.Object, e As System.EventArgs) Handles MyBase.Load
'TODO: This line of code loads data into the 'DCGDataSet1.Main' table. You can move, or remove it, as needed.
Me.MainTableAdapter1.Fill(Me.DCGDataSet1.Main)
End Sub
This is the non-working DS
This is the working DS

Answer 1

I think I know what killed the Handles.  I was playing with a custom Control that created a Currency TextBox, when I found the Control didn't do what I wanted to, I deleted the Class, code and Control from my project.  Apparently in doing
so it also removed all calls to Handles, not sure why, but I am going to work on replicating the issue.
The reason I was asking was this:
When you create an event handler sub, then for whatever reason you delete that control (maybe cut it, then go to paste it elsewhere, or for whatever reason), it will immediately remove the Handles clause.
If you think about it, that's good. The sub is still there (you might use AddHandler rather than a Handles clause), but it can't access that control any longer because it's no longer there! Even for just a split second, if it doesn't exist, it removes that
Handles clause.
Still lost in code, just at a little higher level.