Every time Firefox asks me to install the latest version on my MacBookPro Version 10.5.8 Firefox goes mad, opens prob.10 times and puts my Mac in an inoperable state. I can only restart to get in functioning, but still, can't update to Firefox 4. Help?

Firefox keeps asking me to update to version 4. When the installing process begins, Firefox starts flashing, my MacBook does not respond, the coursor does not respond. I have to shut down completely.

I assume you don't have a backup on an external HD. You always should, because then you could easily fix your problem.
Boot in Safe Mode. See What is Safe Boot, Safe Mode? (Mac OS X)
http://docs.info.apple.com/article.html?artnum=107392 Takes a while to run, but it usually "fixes" problems.
Safe Boot takes longer than normal startup
http://support.apple.com/kb/TS1884?viewlocale=en_US
 Cheers, Tom

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