Help needed getting a USB to serial adaptor to work

I have a new Mac Mini  but an not getting my serial adaptors to be seen by the OS  (10.7)
Any ideas please

Here’s a way to get you PL2303-based Serial-USB adapter working with OS X Lion (10.7). Based on the osx-pl2303 project on github, I’ve built a kernel extension that works with OS X Lion. You can grab the kext file here or from the link below.
Installing the kext file can be done in a few easy steps:
download and extract
cd /path/to/osx-pl2303.kext
cp -R osx-pl2303.kext /System/Library/Extensions/
next you need to fix permissions and execute bits:
cd /System/Library/Extensions
chmod -R 755 osx-pl2303.kext
chown -R root:wheel osx-pl2303.kext
cd /System/Library/Extensions
kextload ./osx-pl2303.kext
kextcache -system-cache
Good luck!

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