ISE certifiacte issue

Hi,
I have a ISE certifiacte issue when I try to authenticate wireless user with ISE. He show me this: 
12321 PEAP failed SSL/TLS handshake because the client rejected the ISE local-certificate12321 PEAP failed SSL/TLS handshake because the client rejected the ISE local-certificate
Please can you help me?
Regards
Aristide

This pretty much means that the authenticating client is not trusting the certificate that is installed in ISE. That certificate is used to build the EAP tunnel that would be used to pass the PEAP credentials. So a couple of questions:
1. What certificate do you have installed in ISE for EAP?
2. What certificate is  the supplicant set to trust

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