My mouse can not click to anything left, right or the middle mouse button does not work

I am using a 24 inch imac and the problem is suddenly my mouse can not click to anything left, right or the middle mouse button does not work i can see cursor moving and i can use the features of the keyboard but my mouse dies. I tried to plug in another mouse magic trackpad and my tablet but each has the same problem. I can not click to anything but cursor is moving and computer is not frozen. I have to shut it off from the power button when this happens. Do you have any idea what can cause this and how can i fix this?

Reset the SMC 2-3 times. Click Intel iMac SMC and PRAM resets for instructions.

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My mouse can not click to anything left, right or the middle mouse button does not work

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