Need 1200 digital outputs that can be updated at 1 MHz

I need to control about 1200 digital outputs (CMOS or TTL)  at high speed (1 MHz).  Any platform
that gets the job done is OK, but I usually program in a WinXP environment.   I also have a problem
of distributing these signals to many units over a roughly 50 by 50 foot area, so I also need hardware
to either drive the outputs over an extended length of wire or to wirelessly distribute the signals to
multiple substations which each operate between 10 and 50 units.
A small number of inputs (maybe just two) would be very useful to control the timing of the
state transitions.

Thanks for  your response.
Our application is controlling LED's for a computer graphics application.
http://gl.ict.usc.edu/Films/RelightingHumanLocomotion/index.html has
some pictures of the apparatus, as well as a short video showing how
it works and the results we've got so far.
The basic idea is to capture varying illumination conditions extremely
rapidly using high-speed (Vision Research) cameras that go at 5000 fps
or so.  The signals that drive the lights are just 5V DC,
currently supplied by a large number of PICS, but we are hoping to find
a more
centralized solution, as well as a higher performance solution (large
program memory for many lighting patterns, high speed processing to
support flexible computation of patterns, high speed updating of
outputs to allow for multiple on/off states within a single 200 usec
interval
to simulate grayscale control of the LED's).
If the system is fast enough, it is possible that a smaller number of
outputs could drive a large bank of latches that provide the final
outputs,
but ideally this would be handled by the NI hardware.  In other
words, we would just buy enough output units, hook them up, and then the
programmer just sets the 1200 bits of memory as desired and then triggers the refresh.
To distribute the signals, one possibility is to have output units with
between 10 and 50 outputs that can be connected to the central
controller with long cables (up to 40 feet) and which in turn drive
individual lights through wires about 10 feet long.  Wireless
would be
even better if it exists.

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