Preflight makes Indesign CS6 run slow?

Hi
I have problems with my indesign CS6. It takes a lot of time until files "let" me start working on them - Around 1 minute and more.
No matter the size of the file.
I've noticed that during all the time I'm waiting for a file to let me work on him; the Preflight is running. To check that, I've disabled preflight and it seems to help, but not all the time. there are still "hang" (The beachball clock is running) from time to time, especially if I'm going to another application and getting back to indesign.
I've also removed all plugins in the plug-n manager in my Font Explorer Pro 3.5.2 but that didn't solve anything.
This is very annoying and frustrating because i have a new iMac, with upgraded Graphic card and new CS6 Design and Web Premium.
The Machine I use is:
NVIDIA GeForce GTX 650
MacOs 10.8.3
  Model Name:
iMac
  Model Identifier:
iMac13,1
  Processor Name:
Intel Core i7
  Processor Speed:
3.50 GHz
  Number of Processors:
1
  Total Number of Cores:
4
  L2 Cache (per Core):
256 KB
  L3 Cache:
8 MB
  Memory:
16 GB
  Boot ROM Version:
IM131.010A.B05
  SMC Version (system):
1.30f3
  Serial Number (system):
C02LH7CQDNCT
  Hardware UUID:
E3732BD5-146F-5DCD-8B8C-AB8BE3BFFA05
David

No, not exactly.
While you work on them, the ID files are in memory (RAM) and it doesn't really matter where they are saved except during read or write operations (save, open, checking links). But ID can only address a bit less than 4 gb of RAM, so at some point a portion of what's in memeory must be written to temporary storage on a disk someplace -- the scratch disk -- where it can be swapped in and out of active RAM when needed. In Photoshop and Illustrator you can designate any drive, even more than one drive, to use for scratch space, but not in ID.
As I said, in Windows it uses the temp folder in your user profile, which by default is on the drive where you installed the OS (but can be moved with some work). On Mac I don't know for sure, but I presume ID is using the user library, which I also presume is on the drive with the OS by default. It looks to me like this is know as the Home Folder, but I'm not a Mac expert. I did find a lot of potential information though, but googling "move user library mac" without quotes.
If you can move your home off the hard drive you might see a difference, but I won't swear to it, and I'd defintiel advise doing a full backup so you can undo any changes you make in case of bad results.

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