Problem with using mouse scrollwheel within CS5?

Hey all. Just upgraded my PS from CS3 to CS5, and I seem to be running into issues with the scrollwheel on my mouse.
When trying to use it from inside CS5 (say, inside a long 'Open...' window), it seems to lock up the entirety of Photoshop for a moment or two every few seconds. Checking the net out there, it looks like there appeared to be a problem with mouse wheels, but that was supposedly fixed nearly a year ago.
I checked for any updates or patches, but the most recent update I can see on the Adobe site is to 12.0.4, which has me doubly confused, as my copy of CS5 say that it is version 12.1, which, theoretically, is a more recent copy...?
I can provide system info, etc. if needed, but since I have not found anything along these lines since a year ago, I'm guessing there's probably some simple thing I'm missing somewhere.
Thanks in advance,
Steve M

You mean Photoshop plugins? No, the version of CS5 I'm having issues with is fresh as a daisy, just digitally downloaded and run for the first time earlier today. I think my old copy of CS3 has some, however, although since they are not being loaded into CS5 (presumably) I'm guessing those wouldn't be the culprit. If this helps any:
Model Name: Mac Pro
Processor Name: Quad-Core Intel Xeon
Processor Speed: 3.2 GHz
L2 Cache (per processor): 12 MB
Memory: 4 GB
System Version: Mac OS X 10.5.8 (9L30)
I'm using a Logitech Performance Mouse MX.
Thanks,
Steve M

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