Run on a Windows 64-bit operating system either as a native application or under WOW64

I am using Visual Studio 2013 Professional, and need to compile my application in a way that it works with existing libraries on my system that are only 32 bit.
I read this someplace ....   "When you compile an application, you can specify that it should run on a Windows 64-bit operating system either as a native application or under WOW64 (Windows 32-bit on Windows 64-bit). WOW64 is a compatibility
environment that enables a 32-bit application to run on a 64-bit system. WOW64 is included in all 64-bit versions of the Windows operating system."
Can anyone tell me HOW I "specify that it should run on a Windows 64-bit operating system either as a native application or under WOW64 (Windows 32-bit on Windows 64-bit)."  ?

Hi Davepc,
Based on your issue, I think the pvdg42 and Wyck's suggestion are really help you. So if possible, I suggest you can try their suggestions to check your issue.
In addition, I get some useful message from the MSDN document, I assume that it maybe useful for you.
(1)So if your application is VB, I suggest you can refer the following document to check your issue.
https://msdn.microsoft.com/en-us/library/8ck8e1y2(v=vs.110).aspx
(2) If your application is c#, please refer to:
https://msdn.microsoft.com/en-us/library/zekwfyz4(v=vs.110).aspx
(3)If your application is c++, please see:
https://msdn.microsoft.com/en-us/library/h2k70f3s(v=vs.80)
Hope it help you!
Best Regards, 
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