When using GPIB hardware, do I need the exact driver[HP-​3478a] or can I use simple raw GPIB-read or 488.2-read commands to take measuremen​ts?

If so, which would I use in order to take a reading from a lab instrument?
GPIB-read or 488.2-read commands to take measurements?

GPIB and 488.2 are the same thing, so the question if kind of moot. If you have a driver for the instrument then that's the best place to start, as it's quite likely to have been debugged and worked out. You can, however, code up your own communication. You would want to use VISA rather than the lower-level 488.2 commands, as this is the preferred API for programming. VISA is just a layer that sits on top of GPIB and allows you to write code so that you can communicate with a device via a serial or GPIB interface.
You should take a look at the examples that ship with LabVIEW as there's a couple that do basic communication using VISA functions.

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