Cannot open iTunes after updated to 10.5

I updated from 10.3 to 10.5 yesterday and I can't open itunes at all.
when I click iTunes, the message pops up, says
'This iTunes has not been correctly configured'
what does that mean? and what should I do??
please reply with a solution!!

oh by the way, I am using iMac OS X version 10.7. if this info helps..

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