Any time I click on a new link, Firefox responds with "Oops! Firefox could not find..." - I click refresh and it loads. Is there a fix for this issue?

This has been happening for a few weeks. I have recently upgraded Firefox to 4.0 hoping that would rectify the problem, but I am still encountering it.

Do you actually mean FastMail? operamail.com simply redirects to fastmail.fm.
The steps for adding a new mailto handler are described in the FastMail wiki:
* http://fastmail.wikia.com/wiki/Firefox_3_default_mailto
If you actually meant mail.opera.com, that's a separate service. In that case, the correct step 5 should be
<pre><nowiki>javascript:window.navigator.registerProtocolHandler("mailto","https://mail.opera.com/m/mail/compose:to=%s","My Opera Mail")</nowiki></pre>
Once you've added the new handler, make sure it's selected as the action for ''mailto'' under Options - Applications.
* [[Set how Firefox handles different types of files]]

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