Cannot write reply email: help!

When I click on "Reply" to a message, the content is blank and I cannot write in it whereas I could see the original message. This has happened the past couple of days.
Also, when I tab from 'To:' to the message, the tab ends at the 'Signature' drop-down then nothing. I cannot write a reply not see the original message.
Also, recently, I have been getting a message while viewing some emails that "the message has not been downloaded from the server. Take it online" when it is online. I have to create a new mailbox then drag all emails into it, deleting the old mailbox. Then I rebuild and can see the messages and function as normal.
Please help and thanks.
MacBook Pro Core 2 Duo   Mac OS X (10.4.8)   Mail 2.1.1

The main problem you mention is probably caused by some Launch Services cache or preferences corruption, but it looks like you could have some filesystem corruption as well, so be sure to verify/repair the disk with Disk Utility first (not just permissions), as described in the second article below.
The following article describes how to manually reset Launch Services -- the notes at the bottom of the article also provide information about the side effects of deleting each of the files involved:
Resetting Launch Services
If you prefer using a cache cleaning utility instead of following the manual procedure described in the previous article, this other article provides links to some utilities that can be used for troubleshooting and cache cleaning:
Resolving Disk, Permission, and Cache Corruption
It seems that the most appropriate utility for solving this particular problem is Tiger Cache Cleaner, but you may also want to consider other utilities, such as OnyX, or Cache Out X, which are free. Whatever utility you choose, be sure to read this first:
Side effects of System cache cleaning
As an example, this is how you should proceed with OnyX:
1. Quit all applications.
2. Launch OnyX and enter your administrator password.
3. Click Maintenance. In the Reset section, check LaunchServices database.
4. You may uncheck any other pre-checked options if you wish.
5. Click the Execute button.
6. Restart the computer.

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