Edit in Photoshop CS6 not working

I recently upgraded to lightroom 5 and CS6 and for some reason I can no longer us the "edit in CS6" option.  Lightroom will go as far as to open photoshop, but won't open the image which I have set to open as an 8bit PSD sRGB.  Any ideas?
Thanks in advance.

paul zimmerman wrote:
Sorry, what i meant by user accounts is this.
On my Imac, i've created 2 user accounts.  User A and User B. when I log in as User A and use lightroom and CS6 everything works fine.  When I log in as User B, I have the issue with lightroom not opening raws in photoshop.  Both users are using the system applications.
Ah, OK so I assume the admin account works, the other doesn't? Have to say I'm not savvy enough to understand what Photoshop/LR need in terms of items in the main account to make this all work. I might have to try that test on this end as I have two accounts too. I use the 2nd for trouble shooting. I suspect the primary account has something, somewhere in the user Library installed by Adobe that is accessed where it might not be in account #2.
If one account works, the other doesn't, we have to pinpoint what files are missing from the account that doesn't work.

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