Excel file save error: Someone else is working in file right now. Please try again later.

When trying to save a modified Excel file, which has been opened from a network share, our users are receiving the following message:
Someone else is working in "\\domain.com\users\username\Document.xls" right now. Please try again later.
The clients that have been affected are Windows 7 clients, and the DFS share is being served from a Windows 2012 server. I have already confirmed that DFS replication has not been enabled, so it isn't trying to lock files for replication. I have also disabled
any real-time scanning that is occurring on the client to make sure that the AV software wasn't locking the files. I did notice when viewing the list of Open Files from the server's Computer Management console that when a users experiences this issue the file
appears to be opened 4 times. Three times it shows that it was opened in Read mode and the 4th instance shows an Open Mode of Write. Typically, a file which is working correctly should just show one instance with the Open Mode of Read+Write. None of these
open instances are temporary files preceded with a ~.
Any thoughts?

Hi,
Does the issue occur in other operation system? Which Office version are you using? Have you ever tried to test with word document, PPT file or txt file?
Based on your description, the issue may be caused by the same file open multiple time in computer management on SQL server. The user probably has User Access Control (UAC) enabled on the machine and it is not letting him overwrite the existing
copy of the file because she does not have it open in administrator mode. UAC will block overwriting (saving) the existing file without Administrative privileges and it will automatically open the save as dialog so you can save with a different name and
if you click save without changing the name at the point, it tries to save as a new file over the existing file and it can't because the file is open.
I recommend you check the user's permission (Which showed in Computer Management console) and end the Excel file instance in the task manager of the user's client.
Also, we may try the workaround: Save it to local drive(like drive c:) and then copy it to DFS.
Thanks
George Zhao
Forum Support
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